What to do? Week 15 Fantasy Football?

I like Tim Hightower over Ganther. I know he splits carries and is a fumble liability but they are playing the Lions who have nothing to play for and have a terrible defense. Once the Cardinals get up on the Lions then they will have a huge run game. I think Eli Manning is a solid back up QB and you should play him for sure if Peyton does not start. Eli threw the ball well against a really tough PHI defense so I would not be worried about playing him if Peyton is not going to play. A defense that looks really good are the 49ers. They rocked the Cards last night and I picked them up in my league. So it just depends on who is available really.